Quality Control Design in Mass Spectrometry Proteomics
Scaling mass spectrometry proteomics requires careful monitoring of both sample processing and instrument performance. Many times, this is performed after the fact via dataset normalization, outlier detection, and other statistical methods to control for data quality. Using Panorama, we have designed a prospective workflow for sample quality control and system suitability to monitor data as it is being acquired to quickly diagnose and troubleshoot production issues.